刘文广 教授
先进高分子材料研究所
电话： 85356417
Email： wgliu@tju.edu.cn
研究所： 先进高分子材料研究所
个人简历
教育背景：
1996年6月-1999年4月 天津大学材料科学与工程学院 生物医学工程专业 博士
1993年9月-1996年3月 天津大学应用化学系 高分子材料专业 硕士
1987年7月-1991年9月 天津大学应用化学系 高分子化工专业 学士
工作经历：
2007年7月-至今 天津大学材料科学与工程学院教授
1999年7月-2007年6月 天津大学材料科学与工程学院 讲师、副教授
2005年3月-2006年11月 加拿大渥太华大学 博士后
2004年3月-2004年11月 香港理工大学 Research Associate
2003年7月-2004年1月 香港大学医学院骨科系访问学者
研究方向
1、再生医学相关生物医用高分子材料
2、高强度水凝胶的设计及其生物医学应用
3、生物医用黏合剂
4、功能高分子材料
标志性成果
主要学术成就、获奖及荣誉：
刘文广，天津大学讲席教授，二级教授，博士生导师，国家杰青，国务院特殊津贴专家，中国生物材料学会理事，中国生物材料学会组织工作委员会委员，中国生物材料学会医用高分子分会副主任委员，国际生物材料科学与工程学会联合会Fellow，Science China Technological Sciences（SCI收录，JCR一区）,《中国科学:技术科学》，《高分子学报》（SCI收录）编委。主要从事生物医用高分子材料的研究，主持和参加国家自然科学重点/面上项目、科技部重点研发、科技创新2030重大项目。创建了基于侧链氨基酸多重氢键交联的超分子聚合物水凝胶，促进和推动了N-丙烯酰基甘氨酰胺（NAGA）的生产和应用；提出了自增稠/自增强3D打印超分子水凝胶墨水的设计理念，并定制了个性化3D打印半月板、角膜替代物；提出了构筑水下和湿态环境应用黏合剂的新策略，由此发展了急救用黏合、口腔修复、止血剂及心肌补片；发展了新型辅酶基超分子聚合物弹性体和水凝胶医用黏合剂。曾获得天津市自然科学一二等奖，2006年入选教育部新世纪优秀人才计划，2012年天津市教工先锋岗先进个人，2013年获得国家杰出青年科学基金资助，2015年获得天津市五一劳动奖章，2016年天津市教育系统优秀共产党员，2017年被评为天津大学第十届“我心目中的好导师”，2018年获第十二届冯新德高分子奖。在Nat Commun, Adv Mater, Adv Funct Mater, Prog Poly Sci等期刊发表学术论文260余篇，2018-2023连续入选Elsevier中国高被引学者，获得50余项中国发明专利授权。
代表性论著补充：
1. Zhuoya Wang, Danyang Chen, Hongying Wang, Siyu Bao, Liping Lang, Chunyan Cui，Haotian Song, Jianhai Yang*，Wenguang Liu*，The Unprecedented Biodegradable Polyzwitterion: A Removal-Free Patch for Accelerating Infected Diabetic Wound Healing，Advanced Materials, 2024, DOI:10.1002/adma.202404297.
2.Rong Yang, Biao Wang, Xiaoping Zhang, Yage Sun, Yiming Zhang, Ziyang Xu*, Qiang Yang*,Wenguang Liu*,A Nucleobase-Driven Self-Gelled Hyaluronic Acid-Based Injectable Adhesive Hydrogel Enhances Intervertebral Disc Repair,Advanced Functional Materials, 2024, 2401232.
3.Bo Liu, Hui Li, Fengzhen Meng, Ziyang Xu, Liuzhi Hao, Yuan Yao, Hao Zhu, Chenmin Wang, Jun Wu, Shaoquan Bian, Willima W. Lu,Wenguang Liu*, Haobo Pan*, Xiaoli Zhao*,4D Printed Hydrogel Scaffold with Swelling-Stiffening Properties and Programmable Deformation for Minimally Invasive Implantation,Nature Communications, 2024, 15, 1587.
4. Chunyan Cui#, Li Mei#, Danyang Wang, Pengfei Jia, Qihui Zhou*,Wenguang Liu*, A Self-Stabilized and Water-Responsive Deliverable Coenzyme-Based Polymer Binary Elastomer Adhesive Patch for Treating Oral Ulcer,Nature Communications, 2023, 14, 7707.
5.Chunyan Cui, Yage Sun, Xiongfeng Nie, Xuxuan Yang, Fushuo Wang,Wenguang Liu*,A Coenzyme-Based Deep Eutectic Supramolecular Polymer Bioadhesive,Advanced Functional Materials, 2023, 33, 2307543.
6.Yudi Pang, Hongying Wang, Yuan Yao, Danyang Chen, Rong Yang, Zhuoya Wang, Jianhai Yang*, Yongmao Li*,Wenguang Liu*, An Injectable Self-Crosslinked Wholly Supramolecular Polyzwitterionic Hydrogel for Regulating Microenvironment to Boost Infected Diabetic Wound Healing,Advanced Functional Materials, 2023, 33, 2303095.
7.Puqing Yao, Qiwen Bao, Yuan Yao, Meng Xiao, Ziyang Xu, Jianhai Yang*,Wenguang Liu*，Environmentally Stable, Robust, Adhesive, and Conductive Supramolecular Deep Eutectic Gels as Ultrasensitive Flexible Temperature Sensor,Advanced Materials, 2023, 35, 2300114.
8.Yage Sun, Xiaoping Zhang, Tengling Wu, Zhuodan Zhang, Rong Yang,Wenguang Liu*YAP-Suppressive Nanodrug Crosslinked Self-Immunoregulatory Polysaccharide Injectable Hydrogel for Attenuating Cardiac Fibrosis to Treat Myocardial Infarction，Advanced Functional Materials, 2023, 33, 2214468.
9.Xinyu Bian, Chunyan Cui, Ying Qi, Yage Sun, Zhuodan Zhang,Wenguang Liu*,Amino Acid Surfactant-Induced Superfast Gelation of Silk Fibroin for Treating Noncompressible Hemorrhage,Advanced Functional Materials, 2022, 32, 2207349.
10.Qian Zhang, Ziyang Xu, Xiaoping Zhang, Changjun Liu, Rong Yang, Yage Sun, Yahan Zhang,Wenguang Liu*,3D Printed High-Strength Supramolecular Polymer Hydrogel-Cushioned Radially and Circumferentially Oriented Meniscus Substitute,Advanced Functional Materials, 2022, 32, 2200360.
11. Jiankang He#, Jianhai Yang#, Min Li, Yachong Li, Yanyun Pang, Jiayin Deng*, Xu Zhang*,Wenguang Liu*,Polyzwitterion Manipulates Remineralization and Antibiofilm Functions against Dental Demineralization,ASC Nano, 2022, 16, 3119-3134.
12.Ziyang Xu, Chuanchuan Fan, Qian Zhang, Yang Liu, Chunyan Cui, Bo Liu, Tengling Wu, Xiaoping Zhang,Wenguang Liu*,A Self-Thickening and Self-Strengthening Strategy for 3D Printing High-Strength and Antiswelling Supramolecular Polymer Hydrogels as Meniscus Substitutes,Advanced Functional Materials, 2021, 31, 2100462.
13.Yuan Yao, Ziyang Xu, Bo Liu, Meng Xiao, Jianhai Yang*,Wenguang Liu*,Multiple H-Bonding Chain Extender-Based Ultrastiff Thermoplastic Polyurethanes with Autonomous Self-Healability, Solvent-Free Adhesiveness, and AIE Fluorescence,Advanced Functional Materials, 2021, 31, 2006944.
14.Jing Yu#, Ke Wang#, Chuanchuan Fan, Xiaoye Zhao, Jushan Gao, Wanghui Jing, Xiaoping Zhang, Jia Li, Yuan Li, Jianhai Yang*,Wenguang Liu*,An Ultrasoft Self-Fused Supramolecular Polymer Hydrogel for Completely Preventing Postoperative Tissue Adhesion,Advanced Materials, 2021, 33, 2008395.
15.Chunyan Cui,Wenguang Liu*,Recent Advances in Wet Adhesives: Adhesion Mechanism,Design Principle and Applications,Progress in Polymer Science, 2021, 116, 101388.
16.Chunyan Cui, Ruoheng Gu, Tengling Wu, Zuoying Yuan, Chuanchuan Fan, Yuan Yao, Ziyang Xu, Bo Liu, Jianyong Huang,Wenguang Liu*,Zwitterion-Initiated Spontaneously Polymerized Super Adhesive Showing Real-Time Deployable and Long-Term High-Strength Adhesion against Various Harsh Environments,Advanced Functional Materials, 2021, 32, 2109144.
17.Yanjie Wang, Yang He, Siyu Zheng, Ziyang Xu, Jia Li, Yiping Zhao*, Li Chen*,Wenguang Liu*,Polymer Pressure-Sensitive Adhesive with A Temperature-Insensitive Loss Factor Operating Under Water and Oil,Advanced Functional Materials, 2021, 31, 2104296.
18.Chunyan Cui, Tengling Wu, Xinyu Chen, Yang Liu, Yuan Li, Ziyang Xu, Chuanchuan Fan,Wenguang Liu*,A Janus Hydrogel Wet Adhesive for Internal Tissue Repair and Anti-Postoperative Adhesion,Advanced Functional Materials, 2020, 30, 2005689.
19.Qingfei Liang, Fei Gao, Zhiwen Zeng, Jirong Yang, Mingming Wu, Chongjian Gao, Delin Cheng, Haobo Pan*,Wenguang Liu*, Changshun Ruan*,Coaxial Scale-Up Printing of Diameter-Tunable Biohybrid Hydrogel Microtubes with High Strength, Perfusability, and Endothelialization,Advanced Functional Materials, 2020, 30, 2001485.